Science

Common mistakes in enzymes and digestion

4 mistakes learners make with enzymes and digestion, each one named and explained.

All common mistakes

An enzyme is a catalyst with a shape, and everything that stops it working stops it by changing that shape.

Enzymes said to die

What it looks like

You write that the enzyme died at 60 degrees C.

Why it happens

Enzymes come from living things and they stop working, so dying is the obvious word.

A worked example

Question. What happens to an enzyme heated well above its optimum?

A common answer. it dies

The answer. it denatures: its shape changes so the substrate no longer fits

Why. An enzyme is a protein, not an organism. It was never alive, so it cannot die.

Put the two side by side

Dying is something an organism does.
Denaturing is a change of shape in a molecule.

Say denatured, and then say what changed shape and why that stops it working.

Enzymes thought to be used up

What it looks like

You say the reaction stopped because the enzyme ran out.

Why it happens

Everything else in a reaction gets used up, so the enzyme looks like another ingredient.

A worked example

Question. A reaction catalysed by an enzyme stops. The substrate has all gone. What has happened to the enzyme?

A common answer. it has been used up too

The answer. it is unchanged and ready to work again

Why. A catalyst speeds a reaction up without being used up, which is why a little goes a long way.

Put the two side by side

Substrate is consumed.
Enzyme is not.

If it is used up it is a reactant, not a catalyst.

Monomers paired with the wrong polymer

What it looks like

You say protein breaks down into glucose, or starch into amino acids.

Why it happens

The words are learned as two separate lists, and nothing in them says which pairs with which.

A worked example

Question. What does protein break down into?

A common answer. glucose

The answer. amino acids

Why. Starch gives glucose, protein gives amino acids, and lipids give fatty acids and glycerol.

Put the two side by side

Starch is a chain of glucose.
Protein is a chain of amino acids.

Learn each polymer with its monomer attached, as a pair, never as two lists.

One enzyme expected to work on many substrates

What it looks like

You say an enzyme in the gut breaks down food, without saying which kind.

Why it happens

Digestion is one process from the outside, so one worker for the whole job seems reasonable.

A worked example

Question. Can amylase break down protein?

A common answer. yes, it is a digestive enzyme

The answer. no. Its active site fits starch and nothing else

Why. The shape of the active site is what matches one substrate, so each enzyme has one job.

Put the two side by side

One enzyme, one kind of substrate.
A different substrate needs a different enzyme.

Name the enzyme and the substrate together, or the answer is not finished.

WAJD spots these patterns in your child's answers and names the one behind their wrong answers, instead of just marking them wrong.

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